Malegra 100 contains sildenafil citrate, which is a PDE5 inhibitor. It works by relaxing the blood vessels in the penis, allowing increased blood flow, which helps men achieve and maintain an erection. Malegra 100 is widely used to treat ED and is considered effective for many men. However, it may not always work as expected for everyone. In such cases, combining Malegra 100 with other therapies may be recommended to enhance its effects.