Opana exerts its action mainly by binding with opioid receptors in the brain and spinal cord. In so doing, it changes the way the body perceives pain. This mode of action provides very potent pain relief and is, therefore, highly useful for patients in post-surgical pain, cancer-related pain, or severe injuries.

1. Dosage:
   IR Opana: 5mg to 10mg every 4 to 6 hours as needed for analgesia.
   ER Opana: Generally initiated at 10mg every 12 hours,
   Maximum Dose: The dose should be maintained according to the tolerance and medical history of the patient,

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