Tadalista 40 mg is taken orally, about 30 to 60 minutes before sexual activity. Its effects can last up to 36 hours, offering a longer window of opportunity for intimacy. However, due to its higher potency, the risk of side effects is also increased. Common side effects include headache, flushing, nasal congestion, indigestion, back pain, and muscle aches. Serious side effects may include changes in vision, chest pain, or prolonged erections and require immediate medical attention.